Compound guides

Full guides to 31 compounds. Each one covers how the compound might work, what the studies found, what is known about safety and every source.

Bioactive
Index
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Metabolic & GLP-1

  • 5-Amino-1MQ Lab-made small molecule that blocks the enzyme NNMT. Tested in cells and mice for effects on body fat and metabolism, with a link to how cells make NAD+. Preclinical
  • Cagrilintide Long-lasting copy of the hormone amylin. Tested in trials up to phase 3 for appetite and body weight, both alone and together with semaglutide. Phase 3 Clinical
  • Retatrutide Once-weekly peptide still under study. It switches on the GLP-1, GIP and glucagon receptors and has been tested in trials up to phase 3 for body weight and blood sugar. Phase 3 Clinical

Growth Hormone Axis

  • AOD-9604 A lab-made copy of the tail end of human growth hormone. Tested for fat release without the hormone's effects on IGF-1 and blood sugar. Phase 2 Clinical
  • CJC-1295 No DAC A 29-amino-acid copy of GHRH with four swaps that slow its breakdown. It lacks the DAC linker that binds albumin, so it acts for hours, not days. Preclinical
  • CJC-1295 with DAC A GHRH copy with a Drug Affinity Complex that binds albumin in the blood. The add-on makes it last much longer than the short-acting No DAC form. Preclinical
  • Follistatin 344 A form of follistatin that binds and blocks myostatin and activin. Tested in animals, mostly by gene delivery, for muscle growth. Preclinical
  • IGF-1 LR3 A lab-made IGF-1 that binds weakly to IGF-binding proteins, so more of it stays free. Used to study growth signals in cells and small animals. Preclinical
  • Ipamorelin A five-amino-acid peptide that switches on the ghrelin receptor (GHSR-1a). It released growth hormone with little effect on cortisol, ACTH or prolactin. Preclinical
  • Ipamorelin + CJC-1295 Ipamorelin acts on the ghrelin receptor and CJC-1295 No DAC on the GHRH receptor. Similar pairs released more growth hormone than the sum of each alone. Preclinical
  • Tesamorelin A lab-made form of GHRH, FDA approved for HIV-related lipodystrophy. It cuts deep belly fat by raising the body's own growth hormone. Approved Pharma

Tissue Repair & Recovery

  • ARA-290 An 11 amino acid peptide copied from EPO that does not raise red blood cells. Tested in Phase 2 trials for small fiber nerve damage and tissue protection. Phase 2 Clinical
  • BPC-157 Lab-made peptide copied from a protein in stomach juice. Tested in more than 100 animal and cell studies for healing of tendon, muscle and the gut. Preclinical
  • BPC-157 + TB-500 A pairing of two repair peptides that act in different ways. Each has animal research of its own, but no published study has tested the pair. Preclinical
  • GHK-Cu A three-amino-acid peptide that carries copper. Hundreds of cell and animal studies tested it for collagen, wound healing and gene activity. Preclinical
  • Glow A pen that holds GHK-Cu, BPC-157 and TB-500. Each was tested alone in cells and animals. The three have never been tested together. Preclinical
  • KPV The lysine, proline and valine tail of alpha-MSH. Tested in cells and animals for effects on inflammation, mostly in the gut. Preclinical
  • TB-500 TB-500 copies the active part of Thymosin Beta-4. A wide body of animal research tested it for cell movement, new blood vessels and wound healing. Preclinical

Cognitive & Nootropic

  • DSIP A chain of nine amino acids first found in rabbit blood during deep sleep. Tested for sleep, stress hormones and pain. How it works is still unknown. Early Clinical
  • Selank Selank is a lab-made copy of the immune peptide tuftsin with a stabilizing tail. Russia approves it as a nasal spray for anxiety. Most studies used animals. Approved Pharma
  • Semax Semax is a seven amino acid peptide made from a piece of ACTH. Russia approves it for stroke and thinking problems. Animal studies link it to higher BDNF. Approved Pharma

Longevity & Mitochondrial

  • Epithalon Epithalon is a four amino acid peptide (Ala-Glu-Asp-Gly). Scientists have tested it in cells and rodents for effects on telomerase, the pineal gland and lifespan. Preclinical
  • Glutathione Glutathione is the main antioxidant that cells make. Small human trials have tested supplements for redox balance and detox, with mixed results. Human RCTs
  • MOTS-c A 16-amino-acid peptide coded in mitochondrial DNA. Tested in mice and small human groups for AMPK signaling, blood sugar control and exercise-like effects. Preclinical / Early Clinical
  • NAD+ A coenzyme that cells need for energy, DNA repair and sirtuin enzymes. Evidence runs from basic chemistry to small human trials with mixed results. Mixed Evidence
  • SS-31 A lab-made peptide (elamipretide) that binds cardiolipin in mitochondria. Tested in animals and human trials for how well mitochondria make energy. Early Clinical

Immune, Endocrine & Melanocortin

  • Kisspeptin A small brain protein from the KISS1 gene that tells the body to release GnRH. Tested in early human trials on fertility, IVF and late puberty. Early Clinical
  • Melanotan 2 A lab-made ring of seven amino acids that switches on four melanocortin receptors at once. Studied for skin pigment. Its wide reach is behind the safety worries. Human Trials
  • Oxytocin A hormone of nine amino acids that is also an approved medicine. Scientists study its links to social behavior, stress and the body. Approved Pharma
  • PT-141 Bremelanotide, a ring-shaped peptide that favors the MC4R receptor. FDA approved for low sexual desire disorder in women. Studied for how the brain drives arousal. Approved Pharma
  • Thymosin Alpha-1 A 28 amino acid thymus peptide tested for T cell growth, TLR signaling and fighting viruses. Approved in several countries for hepatitis B and C and immune uses. Approved Pharma